triclosan
Place in Therapy
Place in Therapy
Triclosan is an antibacterial/antimicrobial agent that is found in dentifrices and mouthrinses. It inhibits the enzyme enoyl-acyl carrier protein reductase that is essential for bacterial fatty acid synthesis. Triclosan blocks this enzyme and prevent the formation of cell membrane leading to cell death in bacteria.
Triclosan was shown to effectively prevent supragingival calculus and reduce dental plaques in many randomized control trials lasting from 10 weeks to six months. The triclosan/copolymer dentifrices were more effective in reducing gingivitis and plaque than a fluoride dentifrice. Brushing teeth with toothpastes containing triclosan/copolymer twice a day was associated with reduction of plaques and preventing tartar formation.
References:
Davies RM, Ellwood RP, Davies GM. The effectiveness of toothpaste containing Triclosan and PVM/MA in improving plaque control and gingival health. A systemic review. J Clin Periodontol. 2004; 31: 1029-1033.
Triclosan is an antibacterial/antimicrobial agent that is found in dentifrices and mouthrinses. It inhibits the enzyme enoyl-acyl carrier protein reductase that is essential for bacterial fatty acid synthesis. Triclosan blocks this enzyme and prevent the formation of cell membrane leading to cell death in bacteria.
Triclosan was shown to effectively prevent supragingival calculus and reduce dental plaques in many randomized control trials lasting from 10 weeks to six months. The triclosan/copolymer dentifrices were more effective in reducing gingivitis and plaque than a fluoride dentifrice. Brushing teeth with toothpastes containing triclosan/copolymer twice a day was associated with reduction of plaques and preventing tartar formation.
References:
Davies RM, Ellwood RP, Davies GM. The effectiveness of toothpaste containing Triclosan and PVM/MA in improving plaque control and gingival health. A systemic review. J Clin Periodontol. 2004; 31: 1029-1033.