Genteal gel drops (hypromellose 0.3%)
Place in Therapy
Place in Therapy
Genteal Gel Drops (hypromellose 0.3%) has limited evidence to support its use as a palliative agent in the treatment of dry eye. It has weak primary literature to support its safety and efficacy in the treatment of moderate to severe dry eye syndrome. Despite this lack of evidence, hypromellose is generally considered by secondary and tertiary references to be an acceptable option for the treatment of dry eyes. This is due to the general lack of strong data to support any/most of the agents available for the treatment of dry eye. The preservative found in Genteal Gel Drops (hypromellose 0.3%) is not aggravating, and thus can be considered a good second-line option for patients with transient dry eyes, considered after other products with more supporting evidence have been tried. Generally, hypromellose can be trialed in a patient to determine if the therapy is appropriate. The treatment of dry eye is very individualized and patient preference tends to determine specific product use.
References:
1. Foster CS. Dry Eye Syndrome. Medscape. Updated Dec 16, 2013. Accessed Mar 9, 2014 from
http://emedicine.medscape.com/article/1210417-overview
2. Friesen AM. Dry Eye. Chapter 16 in Patient Self Care Second Ed. Canadian Pharmacists Association 2010.
Ottawa, ON. p. 127-132.
3. Tauber J. Efficacy, tolerability and comfort of a 0.3% hypromelose gel opthalamic lubricant in the treatment
of patients with moderate to severe dry eye syndrome. Current medical Research and Opinion. 2007; 23(11):
2629-2636.
Genteal Gel Drops (hypromellose 0.3%) has limited evidence to support its use as a palliative agent in the treatment of dry eye. It has weak primary literature to support its safety and efficacy in the treatment of moderate to severe dry eye syndrome. Despite this lack of evidence, hypromellose is generally considered by secondary and tertiary references to be an acceptable option for the treatment of dry eyes. This is due to the general lack of strong data to support any/most of the agents available for the treatment of dry eye. The preservative found in Genteal Gel Drops (hypromellose 0.3%) is not aggravating, and thus can be considered a good second-line option for patients with transient dry eyes, considered after other products with more supporting evidence have been tried. Generally, hypromellose can be trialed in a patient to determine if the therapy is appropriate. The treatment of dry eye is very individualized and patient preference tends to determine specific product use.
References:
1. Foster CS. Dry Eye Syndrome. Medscape. Updated Dec 16, 2013. Accessed Mar 9, 2014 from
http://emedicine.medscape.com/article/1210417-overview
2. Friesen AM. Dry Eye. Chapter 16 in Patient Self Care Second Ed. Canadian Pharmacists Association 2010.
Ottawa, ON. p. 127-132.
3. Tauber J. Efficacy, tolerability and comfort of a 0.3% hypromelose gel opthalamic lubricant in the treatment
of patients with moderate to severe dry eye syndrome. Current medical Research and Opinion. 2007; 23(11):
2629-2636.