NYSTATIN
Patient Counselling
Patient Counselling
· Nystatin is a topical and/or intravaginal anti-fungal product that can be used to treat a variety of fungal infections including VVC, however, it is not commonly used as imidazoles are more convenient.5
· It is available at pharmacies upon consultation with a pharmacist.
· It should provide symptomatic relief within 24-72 hours, however, you should continue treatment for the full 14 day course.4
· If there is no symptomatic relief within 7 days, symptoms get worse, or symptoms reoccur within 2 months the patient should see a doctor.4
Pregnancy and Lactation
· It is safe in pregnancy [vaginal (A) / topical (C)] and although excretion in breast milk is unknown it is not absorbed when applied to mucous membranes/intact skin.4
Administration
· Before applying this product the patient should always wash and dry their hands as well as the infected area ensuring the towels are not reused without being washed, and apply clean clothing after use.4
· Nystatin should be used once daily with 1 applicatorful applied intravaginally for 14 days and/or applied topically.1
· It may be best to use this at bedtime to minimize leakage, lay down to insert into vagina.
Adverse Effects
· Nystatin will occasionally cause skin irritation and pruritus2 and very rarely may cause contact dermatitis, SJS or hypersensitivity reactions.4
· Treatment may damage latex condoms, diaphragms and cervical caps.3
· It may also stain clothing yellow so a pad may be used to prevent this.1
Storage
· Store at room temperature, and avoid excessive heat.4
References:
1. Clarity Informatics Limited. (2007). Prodigy Clinical Topics: Candida – female genital. Retrieved June 21, 2012. http://prodigy.clarity.co.uk/candida_female_genital/view_whole_topic
2. Concolaro M, Da Silva M, Martins H, et al. Efficacy of Fluconazole and Nystatin in the Treatment of Vaginal Candida Species. Acta Derm Venereol. 2012; 92: 78-82.
3. FFPRHC, CEU, BASHH. The management of women of reproductive age attending non-genitourinary medicine settings complaining of vaginal discharge. Journal of Family Planning and Reproductive Health Care. 2006; 32(1): 33-42.
4. Lexi-Comp Online. http://online.lexi.com . Accessed June 2012.
5. RxFiles Drug Comparison Charts. 8th Edition. RxFiles 2010. Antifungal Treatment Chart. Page 52.
.
· Nystatin is a topical and/or intravaginal anti-fungal product that can be used to treat a variety of fungal infections including VVC, however, it is not commonly used as imidazoles are more convenient.5
· It is available at pharmacies upon consultation with a pharmacist.
· It should provide symptomatic relief within 24-72 hours, however, you should continue treatment for the full 14 day course.4
· If there is no symptomatic relief within 7 days, symptoms get worse, or symptoms reoccur within 2 months the patient should see a doctor.4
Pregnancy and Lactation
· It is safe in pregnancy [vaginal (A) / topical (C)] and although excretion in breast milk is unknown it is not absorbed when applied to mucous membranes/intact skin.4
Administration
· Before applying this product the patient should always wash and dry their hands as well as the infected area ensuring the towels are not reused without being washed, and apply clean clothing after use.4
· Nystatin should be used once daily with 1 applicatorful applied intravaginally for 14 days and/or applied topically.1
· It may be best to use this at bedtime to minimize leakage, lay down to insert into vagina.
Adverse Effects
· Nystatin will occasionally cause skin irritation and pruritus2 and very rarely may cause contact dermatitis, SJS or hypersensitivity reactions.4
· Treatment may damage latex condoms, diaphragms and cervical caps.3
· It may also stain clothing yellow so a pad may be used to prevent this.1
Storage
· Store at room temperature, and avoid excessive heat.4
References:
1. Clarity Informatics Limited. (2007). Prodigy Clinical Topics: Candida – female genital. Retrieved June 21, 2012. http://prodigy.clarity.co.uk/candida_female_genital/view_whole_topic
2. Concolaro M, Da Silva M, Martins H, et al. Efficacy of Fluconazole and Nystatin in the Treatment of Vaginal Candida Species. Acta Derm Venereol. 2012; 92: 78-82.
3. FFPRHC, CEU, BASHH. The management of women of reproductive age attending non-genitourinary medicine settings complaining of vaginal discharge. Journal of Family Planning and Reproductive Health Care. 2006; 32(1): 33-42.
4. Lexi-Comp Online. http://online.lexi.com . Accessed June 2012.
5. RxFiles Drug Comparison Charts. 8th Edition. RxFiles 2010. Antifungal Treatment Chart. Page 52.
.