Mouth Kote
Place in Therapy
Place in Therapy
Mouth Kote is a saliva substitute spray that seems to lack sufficient evidence in its efficacy for the treatment of xerostomia symptoms. There also appears to be no difference in patient preference and salivary flow as compared to other saliva substitute agents.1,2 The safety and toxicity profile of Mouth Kote also lacks sufficient evidence and, thus, should be used with caution, especially in special populations such as pregnant and lactating women. If patient is pregnant or lactating, the use of Mouth Kote should be discouraged.3 Other saliva substitutes with more evidence for efficacy and with neutral pH should be encouraged over Mouth Kote.4 However, Mouth Kote can still be an option for xerostomia patients if there is a strong patient preference towards the product.
References:
1. Stewart CM, Jones AC, Bates RE, Sandow P, Pink F, Stillwell J. Comparison between saliva stimulants and a saliva substitute in patients with xerostomia and hyposalivation. Spec Care Denstist. Nov 1998; 18(4): 142-148.
2. Furness S, Worthington HV, Bryan G, Birchenough S, McMillan R. Interventions for the management of dry mouth: topical therapies. Cochrane Database Syst Rev. 2011; 12:1-104.
3. Yerba Santa. In: Natural Standard. Sommerville, MA. 2013. http://www.naturalstandard.com. Accessed July 7, 2013.
4. Ganesh F, Baier R, Meyer, A. Tissue-on-tissue lubricity studies of saliva substitutes as supplied, mixed with and compared with human saliva from control and xerostomia patients. IEEE. 2010; 36:1-2.
Mouth Kote is a saliva substitute spray that seems to lack sufficient evidence in its efficacy for the treatment of xerostomia symptoms. There also appears to be no difference in patient preference and salivary flow as compared to other saliva substitute agents.1,2 The safety and toxicity profile of Mouth Kote also lacks sufficient evidence and, thus, should be used with caution, especially in special populations such as pregnant and lactating women. If patient is pregnant or lactating, the use of Mouth Kote should be discouraged.3 Other saliva substitutes with more evidence for efficacy and with neutral pH should be encouraged over Mouth Kote.4 However, Mouth Kote can still be an option for xerostomia patients if there is a strong patient preference towards the product.
References:
1. Stewart CM, Jones AC, Bates RE, Sandow P, Pink F, Stillwell J. Comparison between saliva stimulants and a saliva substitute in patients with xerostomia and hyposalivation. Spec Care Denstist. Nov 1998; 18(4): 142-148.
2. Furness S, Worthington HV, Bryan G, Birchenough S, McMillan R. Interventions for the management of dry mouth: topical therapies. Cochrane Database Syst Rev. 2011; 12:1-104.
3. Yerba Santa. In: Natural Standard. Sommerville, MA. 2013. http://www.naturalstandard.com. Accessed July 7, 2013.
4. Ganesh F, Baier R, Meyer, A. Tissue-on-tissue lubricity studies of saliva substitutes as supplied, mixed with and compared with human saliva from control and xerostomia patients. IEEE. 2010; 36:1-2.