topical antiseptics
Place in Therapy
Place in Therapy
There are two topical antiseptics that may be used to prevent infections in patients with sunburns. The products contain either povidone iodine or chlorhexidine as the active ingredients. After doing a thorough search, there was no literature that showed the use of povidone iodine or chlorhexidine in patients with sunburns specifically. Povidon iodine and chlorhexidine has been evaluated in patients with burns and patients with thermal burns (suburns belong to both of these categories). Additionally, the use of these products in patients with burns or thermal burns has weak evidence. Therefore, it is difficult to recommend topical antiseptics since it is unknown how effective they are.
Chlorhexidine may cause impaired wound healing and povidone iodine can not be used patients with thyroid disorders. These limitations in addition to the lacks of evidence for efficacy do not support the use of topical antiseptics. Therefore, they are not recommended.
Resources
Al-Kaisy AA, Salih SA. Role of the antioxidant effect of vitamin E with vitamin C and topical povidone-iodine ointment in the treatment of burns. Annals of Burns and Fire Disasters 2005;28(1):19-30.
Betadine Topical Preparations. e-Therapeutics. Retrieved from: https://www.e-therapeutics.ca/cps.showMonograph.action?newSearch=true&simpleIndex=brand_generic&simpleQuery=Dexidin&brandExactMatch=false on July 19, 2014.
Lau YS, Brooks P. Innovative use of povidone-iodine to guide burn wound debridement and predict the success of biobrane as a definitive treatment for burns. Adv Skin Wound Care 2014;27(3):111-113.
Omega. Baxedin 0.05% Solution Leaflet Version 2. Retrieved form: http://www.scribd.com/doc/231207416/Baxedin-20-Leaflet-V-01 on July 19, 2014.
Purdue Products L.P. Betadine Solution Product Information. Retrieved from http://www.betadine.com/pdf/Betadine%20Solution%202007.pdf on July 19, 2014.
US National Library of Medicine. Antiseptic Skin Cleanser (chlorhexidine gluconate) liquid. DailyMed. Retrieved from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5577ecbb-cf2c-45e1-a0fb-17df0417eea5 on July 19, 2014.
US National Library of Medicine. Major Povidone Iodine (povidone-iodine) ointment. DailyMed. Retrieved from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bf631ed8-1080-4586-ae54-57b93d0eb158
Wassail J, Cleland H, Campbell F, Spinks A. Dressings for superficial and partial thickness burns. Cochrane Database Syst Rev 2013 Mar 28;3:CD002106.
Warren D. Skin Disorders: Burns. e-Therapeutics. Retrieved from: https://www.e-therapeutics.ca/tc.showChapter.action on July 19, 2014.
There are two topical antiseptics that may be used to prevent infections in patients with sunburns. The products contain either povidone iodine or chlorhexidine as the active ingredients. After doing a thorough search, there was no literature that showed the use of povidone iodine or chlorhexidine in patients with sunburns specifically. Povidon iodine and chlorhexidine has been evaluated in patients with burns and patients with thermal burns (suburns belong to both of these categories). Additionally, the use of these products in patients with burns or thermal burns has weak evidence. Therefore, it is difficult to recommend topical antiseptics since it is unknown how effective they are.
Chlorhexidine may cause impaired wound healing and povidone iodine can not be used patients with thyroid disorders. These limitations in addition to the lacks of evidence for efficacy do not support the use of topical antiseptics. Therefore, they are not recommended.
Resources
Al-Kaisy AA, Salih SA. Role of the antioxidant effect of vitamin E with vitamin C and topical povidone-iodine ointment in the treatment of burns. Annals of Burns and Fire Disasters 2005;28(1):19-30.
Betadine Topical Preparations. e-Therapeutics. Retrieved from: https://www.e-therapeutics.ca/cps.showMonograph.action?newSearch=true&simpleIndex=brand_generic&simpleQuery=Dexidin&brandExactMatch=false on July 19, 2014.
Lau YS, Brooks P. Innovative use of povidone-iodine to guide burn wound debridement and predict the success of biobrane as a definitive treatment for burns. Adv Skin Wound Care 2014;27(3):111-113.
Omega. Baxedin 0.05% Solution Leaflet Version 2. Retrieved form: http://www.scribd.com/doc/231207416/Baxedin-20-Leaflet-V-01 on July 19, 2014.
Purdue Products L.P. Betadine Solution Product Information. Retrieved from http://www.betadine.com/pdf/Betadine%20Solution%202007.pdf on July 19, 2014.
US National Library of Medicine. Antiseptic Skin Cleanser (chlorhexidine gluconate) liquid. DailyMed. Retrieved from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5577ecbb-cf2c-45e1-a0fb-17df0417eea5 on July 19, 2014.
US National Library of Medicine. Major Povidone Iodine (povidone-iodine) ointment. DailyMed. Retrieved from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bf631ed8-1080-4586-ae54-57b93d0eb158
Wassail J, Cleland H, Campbell F, Spinks A. Dressings for superficial and partial thickness burns. Cochrane Database Syst Rev 2013 Mar 28;3:CD002106.
Warren D. Skin Disorders: Burns. e-Therapeutics. Retrieved from: https://www.e-therapeutics.ca/tc.showChapter.action on July 19, 2014.