Long Acting Nasal Decongestants
Place in Therapy
Place in Therapy
Long-acting nasal decongestants are efficacious in providing relief of nasal congestion that accompanies allergic rhinitis. Evidence from primary literature supporting the use of long-acting nasal decongestants in allergic rhinitis indicates that they are effective as adjunctive therapy to a nasal corticosteroid. Oxymetazoline has been shown to reduce the severity of nasal symptoms in allergic rhinitis when added to intranasal fluticasone compared to fluticasone alone.
The major drawback with the use of nasal decongestants is the occurrence of rebound medicamentosa or rebound rhinitis. Evidence suggests that there is no significant increase in rebound rhinitis after use of a long acting nasal decongestant in combination with an intranasal corticosteroid after 10 days. Caution should still be exercised when recommending long-acting nasal decongestants for longer then a 5- day course.
Long-acting nasal decongestants are efficacious in providing relief of nasal congestion that accompanies allergic rhinitis. Evidence from primary literature supporting the use of long-acting nasal decongestants in allergic rhinitis indicates that they are effective as adjunctive therapy to a nasal corticosteroid. Oxymetazoline has been shown to reduce the severity of nasal symptoms in allergic rhinitis when added to intranasal fluticasone compared to fluticasone alone.
The major drawback with the use of nasal decongestants is the occurrence of rebound medicamentosa or rebound rhinitis. Evidence suggests that there is no significant increase in rebound rhinitis after use of a long acting nasal decongestant in combination with an intranasal corticosteroid after 10 days. Caution should still be exercised when recommending long-acting nasal decongestants for longer then a 5- day course.