Mucin
Patient counselling
Like the product example, patient counselling tips also come largely from Saliva Orthana as well as its use in primary literature. Most studies used the spray version of mucin and patients were asked to use this artificial saliva substitute before every meal and before bedtime. If desired, patients may also use mucin when experiences symptoms of dry mouth at other times. In addition, for those preferring to use lozenges, they could potentially also be used in a similar fashion.
Specifically for the mucin spray, patients should shake the bottle before use and then spray inside their mouth to ensure enough mucin has been deposited to cover their whole mouth. They should spray around their mouth and can use their tongue to help spread the mucin. As with most topical products, patients are instructed to wash their hands before and after use. Although mucin has been documented as fairly safe, any mouth irritation/redness or any other uncomfortable symptoms should be reported to the patient’s physician or pharmacist. Patients should also be cautioned that some mucin products may have an unpalatable taste and if this is not tolerable for the patient, they may chose to try other saliva substitute products.
References
1. A.S Pharma: Saliva Orthana. Accessed July 5th 2013. Available at: http://www.aspharma.co.uk/products.htm
2. Bhxt-Johansen , G., Ek A.C, Ganowlak, W., Granerus, A-K., H. von Schenck, Unosson, M, Wiesel, K.. Improvement of oral mucosa with mucin containing artificial saliva in geriatric patients. Arch. Gerontol. Geriatr., 14 (1992) 193-201 193
3. Davies, A. A comparison of artificial saliva and chewing gum in the management of xerostomia in patients with advanced cancer. Palliative Medicine 2000; 14: 197–203
4. Fox, R., Creamer, P. Treatment of dry mouth and other non-ocular sicca symptoms in Sjögren's syndrome. In: UpToDate, Rose, BD (Ed), UpToDate, Waltham, MA, 2013.
5. Momm, F., Jurievna, N., Volegova-Neher1, Jürgen Schulte-Mönting, Guttenberger, R. Different Saliva Substitutes for Treatment of Xerostomia Following Radiotherapy. Strahlentherapie und Onkologie
6. North Bristol NHS Trust. Supportive Care for Renal Patients With Established Renal Failure (ERF): Information for GPs and the District Nurses. Accessed July 6th, 2013. Available at: http://www.nbt.nhs.uk/sites/default/files/filedepot/incoming/Supportive%20Care%20for%20Renal%20Patients%20with%20established%20renal%20failure.pdf
7. Sweeney, MP., Bagg, J., Baxter,WP., Paisley and Aitchison, T.C. Clinical trial of a mucin-containing oral spray for treatment of xerostomia in hospice patients.Palliative Medicine 1997; 11: 225-232.
8. Visch, L., Gravenmade, E.J., Schaub, H., Vanputten, WLJ., Vissink, A. A double-blind crossover trial of CMC- and mucin-containing saliva substitutes. lilt. J. Oral Maxillofac. SlIrg. 1986: 15: 395--400
9. Vander Reijden, W, Vander kwaak, M, Vissink, A , Veerman, E, and Amerongen, V.Treatment of xerostomia with patients with sjogren’s syndrome. ARTHRITIS & RHEUMATISM. Vol. 39, No. 1, January 1996, pp 57-6.
Specifically for the mucin spray, patients should shake the bottle before use and then spray inside their mouth to ensure enough mucin has been deposited to cover their whole mouth. They should spray around their mouth and can use their tongue to help spread the mucin. As with most topical products, patients are instructed to wash their hands before and after use. Although mucin has been documented as fairly safe, any mouth irritation/redness or any other uncomfortable symptoms should be reported to the patient’s physician or pharmacist. Patients should also be cautioned that some mucin products may have an unpalatable taste and if this is not tolerable for the patient, they may chose to try other saliva substitute products.
References
1. A.S Pharma: Saliva Orthana. Accessed July 5th 2013. Available at: http://www.aspharma.co.uk/products.htm
2. Bhxt-Johansen , G., Ek A.C, Ganowlak, W., Granerus, A-K., H. von Schenck, Unosson, M, Wiesel, K.. Improvement of oral mucosa with mucin containing artificial saliva in geriatric patients. Arch. Gerontol. Geriatr., 14 (1992) 193-201 193
3. Davies, A. A comparison of artificial saliva and chewing gum in the management of xerostomia in patients with advanced cancer. Palliative Medicine 2000; 14: 197–203
4. Fox, R., Creamer, P. Treatment of dry mouth and other non-ocular sicca symptoms in Sjögren's syndrome. In: UpToDate, Rose, BD (Ed), UpToDate, Waltham, MA, 2013.
5. Momm, F., Jurievna, N., Volegova-Neher1, Jürgen Schulte-Mönting, Guttenberger, R. Different Saliva Substitutes for Treatment of Xerostomia Following Radiotherapy. Strahlentherapie und Onkologie
6. North Bristol NHS Trust. Supportive Care for Renal Patients With Established Renal Failure (ERF): Information for GPs and the District Nurses. Accessed July 6th, 2013. Available at: http://www.nbt.nhs.uk/sites/default/files/filedepot/incoming/Supportive%20Care%20for%20Renal%20Patients%20with%20established%20renal%20failure.pdf
7. Sweeney, MP., Bagg, J., Baxter,WP., Paisley and Aitchison, T.C. Clinical trial of a mucin-containing oral spray for treatment of xerostomia in hospice patients.Palliative Medicine 1997; 11: 225-232.
8. Visch, L., Gravenmade, E.J., Schaub, H., Vanputten, WLJ., Vissink, A. A double-blind crossover trial of CMC- and mucin-containing saliva substitutes. lilt. J. Oral Maxillofac. SlIrg. 1986: 15: 395--400
9. Vander Reijden, W, Vander kwaak, M, Vissink, A , Veerman, E, and Amerongen, V.Treatment of xerostomia with patients with sjogren’s syndrome. ARTHRITIS & RHEUMATISM. Vol. 39, No. 1, January 1996, pp 57-6.